Healthcare

Downstream Processing Market Worth Nearly US$ 49.67 Bn by 2030

Precedence Research recently published a report on “Downstream Processing Market (By Product: Centrifuges, Dryers, Chromatography Systems, Filters, Evaporators, Others; By Application: Antibodies Production, Antibiotic Production, Hormone Production, Enzyme Production, Vaccine Production; By Technique: Purification by Chromatography, Solid-liquid Separation, Cell Disruption, Concentration, Formulation) – Global Market Size, Trends Analysis, Segment Forecasts, Regional Outlook 2020 – 2027”. Amid the COVID-19 crisis, The global downstream processing market size is projected to reach USD 49.67  billion by 2027 from an estimated USD 17.87 billion in 2019, at a CAGR of 13.65% from 2020 – 2027.

The market revenue/volume with the help of widespread quantitative and qualitative insights, and forecasts of the market. This report presents breakdown of market into forthcoming and niche segments. Additionally, this research study gauges market revenue growth and its drift at global, regional, and country from 2016 to 2027. This research report evaluates downstream processing market on a global and regional level. It offers thorough analysis of market status, growth and forecast of the global downstream processing market for the period from 2016 to 2027. This research study offers historic data for years 2016 to 2027 along with a forecast from 2020 to 2027 based on value.

Downstream processing includes sequence of unit operations utilized to separate, disinfect, and distillate the product. This process regularly defines the economic viability of the process. This process include the succession of operations needed to take biological materials including tissue culture fluid, cells, and plant tissues, and derive homogeneous and clean protein product out of them. Biopharmaceutical downstream processing involves retrieval and decontamination of a drug substance out of natural sources like bacterial or animal cells. This process is appropriate in protein processes or mAb also for production of polysaccharides, oligonucleotides, and numerous vaccines.

Maximum biopharmaceuticals are therapeutic proteins those are formed in living cells via recombinant engineering, and then sanitized from their culture cells or media with the help ofcultured protein purification methods in a multiple stage downstream process. The effectiveness with which cells yield target proteins through the bio manufacturing process has enhanced fundamentally within the last few years, forming pressure on the downstream operations. There are many areas in downstream processes that have to be upgraded and capitalized in such as new chromatography resins that expand the complete purification capacity.

Scope of the Study

This downstream processing market report studies market dynamics, status and outlook especially in North America, Europe and Asia-Pacific, Latin America, Middle East and Africa. This research report offers scenario and forecast (revenue/volume), and categorizes market by players, type, application, and region. This report also studies global market prominence, competitive landscape, market share, growth rate market dynamics such as drivers, restraints and opportunities, and distributors and sales channel.

This research study also integrates Industry Chain analysis and Porter’s Five Forces Analysis. Further, this report offers competitive scenario which comprises collaborations, market concentration rate and expansions, mergers & acquisitions undertaken by companies.

Growth Factors

Escalation in R&D expenditure by biopharmaceutical establishments and uptake in demand for biopharmaceuticals greatly fuels the growth of downstream processing market across the globe. Furthermore, improved demands for novel solutions, cost saving, process optimization, and progress in usage of techniques like centrifuge to distinct biological particles from suspension are some other influences areprompting the growth of downstream processing market. In contrast, requirement for experienced specialists and high price of instruments needed for processing are curtailing the market growth.

A stable upsurge in the recombinant produces and sale for drug quality has compelled the acceptance of downstream processing across the world. The intensification in the perception of large molecules and the biologics is further awaited to motivate the implementation of downstream methodologies.

Report Highlights

  • Asia Pacific is estimated record firmest growth rate during the prediction period in the downstream processing sector. Nations such as India, China, Japan, and South Korea, are likely to motivate the sale for downstream processing products during years to come
  • In 2019, chromatography segment conquered the global downstream processing market revenue with the maximum share of the total market.
  • In 2019, North America acquired maximum market share in downstream processing sector and is projected to maintain this strong hold throughout the valuation period
  • The antibiotic production segment appeared as most dominating application in 2019
  • Growth in of downstream market in evolving countries is powered by substantial funds by vital market performers, cumulative government funding, emergent R&D infrastructure, and mounting proficiency and academic brilliance

Regional Snapshots

North America region emerged as leading marketplace for downstream processing and gathered major chunk of the revenue generated by market in 2019. This is attributed to motivating government funding for the preferment of bioprocess technologies, a substantial escalation in medical outlay, and the existence of vigorous healthcare infrastructure. North America has further perceived foremost cooperative activities and the governance of some of the healthcare giants those are expansively making spending in the R&D of vaccines and biopharmaceuticals.

Incessant technical progressions in the biotechnology sector of the U.S. have led to a substantial upsurge in the trade of recombinant products. It is predicted that there would be a 10-fold upsurge in trades during years to come. Hence, constant invention in the bioprocessing and biotechnology area is anticipated to offer growth boulevardsin the U.S. downstream processing marketplace.

Key Players:

This report also provides detailed company profiles of the key market players. This research report also highlights the competitive landscape of the downstream processing market and ranks noticeable companies as per their occurrence in diverse regions across globe and crucial developments initiated by them in the market space. This research study also tracks and evaluates competitive developments, such as collaborations, partnerships, and agreements, mergers and acquisitions; novel product introductions and developments, promotion strategies and Research and Development (R&D) activities in the marketplace. The competitive profiling of these players includes business and financial overview, gross margin, production, sales, and recent developments which can aid in assessing competition in the market.

Some of the prominent players in the downstream processing market include:

  • BoehringerIngelheim
  • Danaher Corporation
  • Sartorius Stedium Biotech S.A
  • GE Healthcare
  • Merck Millipore
  • Eppendorf AG
  • 3M Company
  • Thermo Fisher Scientific Inc
  • Finesse Solutions Inc
  • Lonza Group

Segments Covered in the Report

By Product

  • Centrifuges
  • Dryers
  • Chromatography Systems
  • Filters
  • Evaporators
  • Others

By Application

  • Antibodies Production
  • Antibiotic Production
  • Hormone Production
  • Enzyme Production
  • Vaccine Production

By Technique

  • Purification by Chromatography
  • Solid-liquid Separation
    • Centrifugation
    • Filtration
  • Cell Disruption
  • Concentration
  • Formulation

By Regional Outlook

  • North America
    • U.S.
    • Canada
  • Europe
    • U.K.
    • Germany
    • France
  • Asia Pacific
    • China
    • India
    • Japan
    • South Korea
  • Middle East & Africa
  • Latin America

Key Takeaways

  • Comprehensive analysis of the downstream processing market trends and shares from 2020 to 2027 at global and regional level to identify growth opportunities and analyze market developments
  • Exhaustive analysis of price trends with respect to resin type and region that are expected to impact the outlook of the global downstream processing market
  • Porters’ Five Forces analysis that highlights the bargaining power of buyers and suppliers to enable stakeholders to make profit-oriented business decisions
  • Extensive market outlook of key geographic regions along with market drivers, inhibitors, current & future market trends, and emerging applications
  • Comprehensive list of key potential clients across major end-use industries in different geographies
  • Thorough import-export analysis  across the globe
  • Regional level production output to comprehend the demand-supply scenario
  • Competitive landscape covers key companies’ profiling, market share analysis, market footprint analysis, competitive business strategies, channels, and competition matrix for key players

TABLE OF CONTENT

Chapter 1. Introduction

1.1. Research Objective
1.2. Scope of the Study
1.3. Definition

Chapter 2. Research Methodology

2.1. Research Approach
2.2. Data Sources
2.3. Assumptions & Limitations

Chapter 3. Executive Summary

3.1. Market Snapshot

Chapter 4. Market Variables and Scope

4.1. Introduction
4.2. Market Classification and Scope
4.3. Industry Value Chain Analysis
4.3.1. Raw Material Procurement Analysis
4.3.2. Sales and Distribution Channel Analysis
4.3.3. Downstream Buyer Analysis

Chapter 5. Market Dynamics Analysis and Trends

5.1. Market Dynamics
5.1.1. Market Drivers
5.1.2. Market Restraints
5.1.3. Market Opportunities
5.2. Porter’s Five Forces Analysis
5.2.1. Bargaining power of suppliers
5.2.2. Bargaining power of buyers
5.2.3. Threat of substitute
5.2.4. Threat of new entrants
5.2.5. Degree of competition

Chapter 6. Competitive Landscape

6.1.1. Company Market Share/Positioning Analysis
6.1.2. Key Strategies Adopted by Players
6.1.3. Vendor Landscape
6.1.3.1. List of Suppliers
6.1.3.2. List of Buyers

Chapter 7. Global Downstream Processing Market, By Product

7.1. Downstream Processing Market, by Product Type, 2020-2027
7.1.1. Centrifuges
7.1.1.1. Market Revenue and Forecast (2016-2027)
7.1.2. Dryers
7.1.2.1. Market Revenue and Forecast (2016-2027)
7.1.3. Chromatography Systems
7.1.3.1. Market Revenue and Forecast (2016-2027)
7.1.4. Filters
7.1.4.1. Market Revenue and Forecast (2016-2027)
7.1.5. Evaporators
7.1.5.1. Market Revenue and Forecast (2016-2027)
7.1.6. Others
7.1.6.1. Market Revenue and Forecast (2016-2027)

Chapter 8. Global Downstream Processing Market, By Application

8.1. Downstream Processing Market, by Application, 2020-2027
8.1.1. Antibodies Production
8.1.1.1. Market Revenue and Forecast (2016-2027)
8.1.2. Antibiotic Production
8.1.2.1. Market Revenue and Forecast (2016-2027)
8.1.3. Hormone Production
8.1.3.1. Market Revenue and Forecast (2016-2027)
8.1.4. Enzyme Production
8.1.4.1. Market Revenue and Forecast (2016-2027)
8.1.5. Vaccine Production
8.1.5.1. Market Revenue and Forecast (2016-2027)

Chapter 9. Global Downstream Processing Market, By Technology

9.1. Downstream Processing Market, by Technology, 2020-2027
9.1.1. Purification by Chromatography
9.1.1.1. Market Revenue and Forecast (2016-2027)
9.1.2. Solid-liquid Separation
9.1.2.1. Market Revenue and Forecast (2016-2027)
9.1.3. Cell Disruption
9.1.3.1. Market Revenue and Forecast (2016-2027)
9.1.4. Concentration
9.1.4.1. Market Revenue and Forecast (2016-2027)
9.1.5. Formulation
9.1.5.1. Market Revenue and Forecast (2016-2027)

Chapter 10. Global Downstream Processing Market, Regional Estimates and Trend Forecast

10.1. North America
10.1.1. Market Revenue and Forecast, by Product (2016-2027)
10.1.2. Market Revenue and Forecast, by Application (2016-2027)
10.1.3. Market Revenue and Forecast, by Technology (2016-2027)
10.1.4. U.S.
10.1.4.1. Market Revenue and Forecast, by Product (2016-2027)
10.1.4.2. Market Revenue and Forecast, by Application (2016-2027)
10.1.4.3. Market Revenue and Forecast, by Technology (2016-2027)
10.1.5. Rest of North America
10.1.5.1. Market Revenue and Forecast, by Product (2016-2027)
10.1.5.2. Market Revenue and Forecast, by Application (2016-2027)
10.1.5.3. Market Revenue and Forecast, by Technology (2016-2027)
10.2. Europe
10.2.1. Market Revenue and Forecast, by Product (2016-2027)
10.2.2. Market Revenue and Forecast, by Application (2016-2027)
10.2.3. Market Revenue and Forecast, by Technology (2016-2027)
10.2.4. UK
10.2.4.1. Market Revenue and Forecast, by Product (2016-2027)
10.2.4.2. Market Revenue and Forecast, by Application (2016-2027)
10.2.4.3. Market Revenue and Forecast, by Technology (2016-2027)
10.2.5. Germany
10.2.5.1. Market Revenue and Forecast, by Product (2016-2027)
10.2.5.2. Market Revenue and Forecast, by Application (2016-2027)
10.2.5.3. Market Revenue and Forecast, by Technology (2016-2027)
10.2.6. France
10.2.6.1. Market Revenue and Forecast, by Product (2016-2027)
10.2.6.2. Market Revenue and Forecast, by Application (2016-2027)
10.2.6.3. Market Revenue and Forecast, by Technology (2016-2027)
10.2.7. Rest of Europe
10.2.7.1. Market Revenue and Forecast, by Product (2016-2027)
10.2.7.2. Market Revenue and Forecast, by Application (2016-2027)
10.2.7.3. Market Revenue and Forecast, by Technology (2016-2027)
10.3. APAC
10.3.1. Market Revenue and Forecast, by Product (2016-2027)
10.3.2. Market Revenue and Forecast, by Application (2016-2027)
10.3.3. Market Revenue and Forecast, by Technology (2016-2027)
10.3.4. India
10.3.4.1. Market Revenue and Forecast, by Product (2016-2027)
10.3.4.2. Market Revenue and Forecast, by Application (2016-2027)
10.3.4.3. Market Revenue and Forecast, by Technology (2016-2027)
10.3.5. China
10.3.5.1. Market Revenue and Forecast, by Product (2016-2027)
10.3.5.2. Market Revenue and Forecast, by Application (2016-2027)
10.3.5.3. Market Revenue and Forecast, by Technology (2016-2027)
10.3.6. Japan
10.3.6.1. Market Revenue and Forecast, by Product (2016-2027)
10.3.6.2. Market Revenue and Forecast, by Application (2016-2027)
10.3.6.3. Market Revenue and Forecast, by Technology (2016-2027)
10.3.7. Rest of APAC
10.3.7.1. Market Revenue and Forecast, by Product (2016-2027)
10.3.7.2. Market Revenue and Forecast, by Application (2016-2027)
10.3.7.3. Market Revenue and Forecast, by Technology (2016-2027)
10.4. MEA
10.4.1. Market Revenue and Forecast, by Product (2016-2027)
10.4.2. Market Revenue and Forecast, by Application (2016-2027)
10.4.3. Market Revenue and Forecast, by Technology (2016-2027)
10.4.4. GCC
10.4.4.1. Market Revenue and Forecast, by Product (2016-2027)
10.4.4.2. Market Revenue and Forecast, by Application (2016-2027)
10.4.4.3. Market Revenue and Forecast, by Technology (2016-2027)
10.4.5. North Africa
10.4.5.1. Market Revenue and Forecast, by Product (2016-2027)
10.4.5.2. Market Revenue and Forecast, by Application (2016-2027)
10.4.5.3. Market Revenue and Forecast, by Technology (2016-2027)
10.4.6. South Africa
10.4.6.1. Market Revenue and Forecast, by Product (2016-2027)
10.4.6.2. Market Revenue and Forecast, by Application (2016-2027)
10.4.6.3. Market Revenue and Forecast, by Technology (2016-2027)
10.4.7. Rest of MEA
10.4.7.1. Market Revenue and Forecast, by Product (2016-2027)
10.4.7.2. Market Revenue and Forecast, by Application (2016-2027)
10.4.7.3. Market Revenue and Forecast, by Technology (2016-2027)
10.5. Latin America
10.5.1. Market Revenue and Forecast, by Product (2016-2027)
10.5.2. Market Revenue and Forecast, by Application (2016-2027)
10.5.3. Market Revenue and Forecast, by Technology (2016-2027)
10.5.4. Brazil
10.5.4.1. Market Revenue and Forecast, by Product (2016-2027)
10.5.4.2. Market Revenue and Forecast, by Application (2016-2027)
10.5.4.3. Market Revenue and Forecast, by Technology (2016-2027)
10.5.5. Rest of LATAM
10.5.5.1. Market Revenue and Forecast, by Product (2016-2027)
10.5.5.2. Market Revenue and Forecast, by Application (2016-2027)
10.5.5.3. Market Revenue and Forecast, by Technology (2016-2027)

Chapter 11. Company Profiles

11.1. BoehringerIngelheim
11.1.1. Company Overview
11.1.2. Product Offerings
11.1.3. Financial Performance
11.1.4. Recent Initiatives
11.2. Danaher Corporation
11.2.1. Company Overview
11.2.2. Product Offerings
11.2.3. Financial Performance
11.2.4. Recent Initiatives
11.3. Sartorius Stedium Biotech S.A
11.3.1. Company Overview
11.3.2. Product Offerings
11.3.3. Financial Performance
11.3.4. Recent Initiatives
11.4. GE Healthcare
11.4.1. Company Overview
11.4.2. Product Offerings
11.4.3. Financial Performance
11.4.4. Recent Initiatives
11.5. Merck Millipore
11.5.1. Company Overview
11.5.2. Product Offerings
11.5.3. Financial Performance
11.5.4. Recent Initiatives
11.6. Eppendorf AG
11.6.1. Company Overview
11.6.2. Product Offerings
11.6.3. Financial Performance
11.6.4. Recent Initiatives
11.7. 3M Company
11.7.1. Company Overview
11.7.2. Product Offerings
11.7.3. Financial Performance
11.7.4. Recent Initiatives
11.8. Thermo Fisher Scientific Inc
11.8.1. Company Overview
11.8.2. Product Offerings
11.8.3. Financial Performance
11.8.4. Recent Initiatives
11.9. Finesse Solutions Inc
11.9.1. Company Overview
11.9.2. Product Offerings
11.9.3. Financial Performance
11.9.4. Recent Initiatives
11.10. Lonza Group
11.10.1. Company Overview
11.10.2. Product Offerings
11.10.3. Financial Performance
11.10.4. Recent Initiatives

Chapter 12. Research Methodology

12.1. Primary Research
12.2. Secondary Research
12.3. Assumptions

Chapter 13. Appendix

13.1. About Us
13.2. Glossary of Terms

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Precedence Research

Precedence Research is a worldwide market research and consulting organization. We give unmatched nature of offering to our customers present all around the globe across industry verticals. Precedence Research has expertise in giving deep-dive market insight along with market intelligence to our customers spread crosswise over various undertakings.

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